Causes of Asthma
The obstruction of airway caused by asthma mainly involves mast cells and eosinophils. If an antigen such as dust mite or pollen infiltrates into the airway, the body's immune system senses it and produces antibody IgE, which acts as a receptor for mast cells in the bronchial tree. As a result, It causes mast cells to secrete various substances that react with the antigen and cause an inflammatory reaction of airways like histamine. On the other hand, eosinophils are activated by the stimulation of substances secreted by mast cells, which in turn cause inflammation of the airways. If this inflammatory reaction causes swelling of the airway mucosa, typical symptoms of asthma that causes airway obstruction will appear.
In collaboration with a team of multinational researchers, the researchers found that the 'IL1RL1' gene is closely related to eosinophil formation, an inflammatory cell that causes asthma.
Symptoms of Asthma
Typical manifestations include dyspnea, coughing, and wheezing, and the chest may feel uncomfortable and may be uncomfortable due to excessive formation of phlegm and sputum. Breathing is short and the lungs are tight, but they are not colored and can not be confused with chronic obstructive pulmonary disease if there is no chance. Severe symptoms can be life-threatening, so if you have a seizure you need immediate first aid.
Diagnosis of Asthma
Because asthma diagnosis is based on the symptoms of the patient, it is important to communicate as much detail as possible to your doctor. The diagnosis includes cough, wheezing, difficulty in breathing, presence of chest tightness, duration and frequency of symptoms, and it is important to know what triggers are.
The incidence of asthma
Treatment and prevention of asthma
First of all, it is good to reduce environmental risk factors, for example, you need to be careful to be exposed to allergenic causes such as house dust mites and pollen. Especially in the spring when there is a lot of yellow dust and pollen, wearing a mask is recommended.
Medication can be divided into symptom relievers (bronchodilators) that expand the narrowed bronchi and disease modifiers to treat drug and allergic inflammation. Symptomatic relief agents include beta 2 agonists to relieve muscle spasms, and xanthine drugs with bronchodilator and anti-inflammatory effects. Although corticosteroids are well known as disease modifying agents, caution is needed because they can cause side effects such as elevated blood pressure, osteoporosis, and gastric ulcer.
Asthma good food, nutrients
Some asthmatic patients are sensitive to sulfites, which are used to preserve the color of food. Since sulfites are present in many fruit concentrates, wine, juices, potatoes, and shrimp, it is best to avoid these foods.
Asthma related research group, patient group
Korea Asthma Allergy Association
Korean Asthma and Allergy Society